ABSTRACT
C-reactive protein is a chronic inflammation factor and a strong predictor of atherosclerosis in hemodialysis patients. The studies have shown that increased levels of intact parathyroid hormone in uremia may cause to lipid metabolism abnormalities, involved in accelerated atherosclerosis in hemodialysis patients. We survey relation between iPTH and high sensitive CRP and carotid intima-media thickness in hemodialysis patients. In this prospective study, serum levels of high sensitive CRP, iPTH, lipoprotein alpha, cholesterol, low and high density lipoprotein, calcium, phosphor, carotid intima-media thickness of 30 hemodialysis patients with ESRD were evaluated. Mean of high sensitive CRP in males was 4.65 mg/dl and in females was 6.4 mg/dl, mean of iPTH in males was 65.7 pg/dl and in females was 74.03 pg/dl. Significant difference was not found between mean of intima media thickness of right and left carotid in two sex [P>0.05]. But, significant correlation was found between high sensitive CRP. iPTH and intima media thickness of carotid [p<0.001]. Attention to this findings, especially using of high sensitive CRP could result in early diagnosis of atherosclerosis. Therefore, it will be decrease of mortality of these pateints